Thursday, October 31, 2019

Analysis of the case of Repulse Travel Pharmaceuticals Coursework

Analysis of the case of Repulse Travel Pharmaceuticals - Coursework Example g title, table of contents, list of tables and figures, bibliography and appendices 16 Bibliography 17 Brigham E F & Ehrhardt, M C 2011 Financial Management Theory and Practice. South-western Cengage Learning, Mason, OH 17 List of tables and figures Table 1 Summary of profit changes vs demand changes 12 Table 2 Summary of profit changes vs price changes 14 Table 3 Profit and loss study under condition of certainty 18 Table 4 Payback period under condition of certainty 18 Table 5 NPV and PI under condition of certainty 18 Table 6 NPV and PI under condition of certainty (Capex & R&D) 18 Table 7 Profit and loss study 1% drop in demand 19 Table 8 Profit and loss study 1% rise in demand 19 Table 9 Payback period 1% drop in demand 19 Table 10 NPV and PI with 1% drop in demand 19 Table 11 NPV and PI with 1% drop in demand (Capex + R&D) 19 Table 12 Profit and loss study 5% drop in demand 20 Table 13 Profit and loss study 5% rise in demand 20 Table 14 Payback period with 5% drop in demand 20 Table 15 NPV and PI with 5% drop in demand 20 Table 16 NPV and PI with 5% drop in demand (Capex + R&D) 20 Table 17 Profit and loss study 1% drop in price 21 Table 18 Profit and loss study 1% rise in price 21 Table 19 Payback period with 1% drop in price 21 Table 20 NPV and PI with 1% drop in price 21 Table 21 NPV and PI with 1% drop in price (Capex + R&D) 21 Table 22 Profit and loss study 5% drop in price 22 Table 23 Profit and loss study 5% rise in price 22 Table 24 Payback period with 5% drop in price 22 Table 25 NPV and PI with 5% drop in price 22 Table 26 NPV and PI with 5% drop in price (Capex + R&D) 22 Figure 1 Graph of profit change vs demand change 13 Figure 2 Graph of profit change vs price change 14 1.0 Introduction This report is in compliance with the coursework case, the topic... Repulse is not certain whether Citronex should be introduced into the market, because the management fears that the financial risks of doing so are substantial. Managers who are convinced that it should cites the potential profits and cash flows the product could bring. In analysing the merits of either side, it is determined that if the product performs as forecasted, Citronex will be profitable; however, it is also risky in that if the demand and price are lower than forecasted by even a small degree, the financial losses are magnified and may be substantial. Repulse Travel Pharmaceuticals, a UK based medium sized firm, is presently deliberating on whether or not it shall launch a new spray product â€Å"Citronex,† which has an estimated five year commercial life. The firm has spent  £150,000 on product and market research on Citronex. The aim of this report is to provide an analysis by which management may decide whether or not the manufacture and sale of Citronex should be undertaken. The report intends to accomplish this task by conducting an estimation, based on forecasted demand and selling price, of the profit and cash flows the company is likely to realize. Its objectives, therefore, include: 1.2.1 an estimation of profit and loss as well as cash flows based on the given information under conditions of certainty on the forecasted demand and selling price 1.2.2 an estimation of profit and loss as well as cash flows based on the given information under the likely conditions that the demand may rise or fall

Tuesday, October 29, 2019

African American Population Essay Example for Free

African American Population Essay At the beginning of each decade in the United States a census is taken to determine the population (Gale, 2008). While the 2000 census states that the African American population makes up 13% of the American population. And predicts it will stay the same percentage until the year 2050. The African American population will reproduce and contribute to the world as other majority and minority groups. So why wouldnt this group grow as a population. African American Growth The African American population has been growing in America since they were involuntarily brought here. From 1492 to 1820 the African American population grew to 9. 5 million in the west alone (POPULATION, 2000). In 1900, there were 8. 8 million African Americans in the United States, representing 11. 6% of the total population. Between 1910 and 1930, the African American population percentage declined, reaching a low point in 1930 when the population was only 9. 7% of the United States population (Gale, 2008). Since 1930, the African American population has grown at a faster rate than national averages (POPULATION, 2000). Over four centuries the African American population has become less rural and concentrated than it was in the nineteenth century (POPULATION, 2000). African Americans do not have to endure slavery. The group has also gained the same rights as other minority and majority groups. The United States Department of Commerce The Department of Commerce expects growth in the Black population. The United States Department of Commerce expects the Black population to make up 16 percent on the American population, by the year 2050 (Black Collegian, 2002). The Department Economic and Statistic Administration will examine effect of the 2010 census and the black population. The Administration will concentrate on the finances of the Black population and any other new aspects to review. The census Bureau The 2000 census states that the African American population makes up 13 percent of the American population (U. S. Census Bureau, 2000). The census also predicts that the African American population will continue to make up only 13 percent in the year 2050 (Census, 2000). The Almanac suggests that African American are ranking lower than any other group in all categories. The almanac reference income gaps between African Americans and other races. The Black, American Indian and Alaskan Native, and Native Hawaiian and Other Pacific Islander populations are expected to maintain their shares of the population in all series (U. S. Census Bureau, 2008 and 2009). A population that is having children and playing a major to the world as all other populations cannot stay the same for a period of 50 years. The encyclopedia of population stated that African American population growth increases much faster than statistics assume. The Department of Commerce predicts the African American population will rise to 16 percent in the year 2050. While the Census Bureau predicts that there will be no increase in the African American population in the year 2050 with out giving details of why this prediction is accurate. African American have endured a great struggle in America. They have over came many obstacles and they will overcome this one also. References POPULATION. (2000). In Encyclopedia of the United States in the Nineteenth Century. Retrieved from http://www. credoreference. com/entry/galeus/populationSmith, M. (2001). Ed. ). (1993). Black Collegian. [University of Phoenix Custom Edition e-Text]. : . Retrieved March 31, 2010Year, from com220. Encyclopedia of population (Ed. ). (2003). African American population History. [University of Phoenix Custom Edition e-Text]. : . Retrieved March 26, 2010Year, from com220. Boyle, K. (2010). The Promise land: The making of African America. Retrived from New York Times book review. Table 1 Type the table text here in italics; start a new page for each table [Insert table here] Figure Captions Figure 1. Caption of figure [Figures – note that this page does not have the manuscript header and page number].

Sunday, October 27, 2019

Looking At Brain Tumors Psychology Essay

Looking At Brain Tumors Psychology Essay Brain tumors are a very harmful diagnoses that can completely change a persons everyday lifestyle. It could change their lifestyle because, the symptoms that come with brain tumors. Also, it can cause personality changes and certain types of body reactions. This illness has a major effect to the patient and can also effect the family. How the brain tumor occurs is when abnormal growth of cells that are forming together. When the cells form together then it can cause a mass of tumor. There are many different types of brain tumors that exist; about 120 types that can affect a human being. Primary and secondary brain tumors can be either malignant or benign. They are also classified in different types of grades, from one to four. They rate the grades from lowest risk to highest risk, one being low risk and four being a higher risk. People that are affected by this diagnosis can cause visual, speech, and hearing change, memory problems, balance and walking problems, etc. When being diagn osis with brain tumor, there are treatments that can help fighting off the disease. The treatments depend on the type of the tumor, but it usually involves with radiation, surgery, and chemotherapy. Brain tumors are a very difficult process that can change everything about a person, or it could even be life threatening to them. The way tumors develop is when cells grow old, have damage, or die off, the body is supposed to form new cells to replace them. Brain Tumors Page Number: 2 During this process certain problems can occur and the body doesnt need the new cells, also the old and damaged cells dont die off when they should be. When this happens the cells will build up forming a mass of tumor, also called the growth of tumors (-oma, tumor) and (oncoma, mass tumor). A brain tumor is a mass of abnormal tissue growing in any part of the brain. Brain cells multiply in an uncontrolled manner and forms these tumors. These tumors can arise from any part of the brain, spinal cord or the nerves. Broadly these tumors can be divided into benign and malignant tumors (Thakur, Gahane, Bhadoriya, Jain S., Jain R., Mishra). Malignant can form cancer that can spread throughout the body, while benign doesnt form any type of cancer or even spread to other parts of the body. Benign tumors has a border edge that the cells barley invade the tissue surrounding them. The possibility for benign to spread to other parts of the body is very slim. The only cause of serious health issue is when the tumor presses on sensitive areas of the brain. A benign tumor can be removed, but they can also grow back. Sometimes a benign tumor can change into a malignant tumor. A malignant tumor can also be called brain cancer. Malignant is way more serious than benign and can also be life threatening. When a malignant tumor is forming it can rapidly grow causing damage to healthy brain tissues. Unlike benign, malignant can break away and spread to other parts of the body. The main parts would be the spinal cord or even other parts in the brain. Brain Tumors Page Number: 3 When dealing with tumors, there are different types of grades that they fall into. The grades are classified from 1 through 4, lowest risk to the highest risk. Grade 1 is normally a benign tumor that grows slowly. A grade 2 is a malignant tumor that has cells that look very different from the grade 1 cells. The third grade is also a malignant tumor that usually anaplastic abnormal cells. The final Grade is a malignant tissue that is in its worst condition. Grade 4 malignant tend to grow very fast when it occurs. Using these terms and definitions will help physicians diagnose people with these types of health problems. When diagnosing, physicians can tell a brain tumor by the way the cells look under a microscope. Brain tumors are often diagnosed on the basis of imaging and processing methods. Generically, the imaging of brain tumors aim to determine the localization, extend, type and malignancy of the pathology (Cruz-Barbosa Vellido). Imaging evaluation includes computer tomography (CT) and magnetic resonance imaging (MRI) that complement each other and describe the tumor location, local extension, compression in the neighborhood structures, superjacent hydrocephalus. Position emission tomography can differentiate recurrent tumor necrosis postoperative scarring or post-therapy edema (Clobanu, Miron, Tansanu, Dumitrescu Indrei). Magnetic Resonance Imaging (MRI) is a common data acquisition technique for Brain Tumors Page Number: 4 this task (Cruz-Barbosa Velliod). These procedures can help the physicians tell that there is a mass of tumor in the brain. It can also show what part of the brain the tumor is occurring and, what kind of tumor it may be. Following the symptoms will help physicians know if their patient is occurring a brain tumor. Usually, the symptoms depend on their type, size, aggressiveness, and the location the tumor is in the brain. There are many different types of symptoms for certain types of tumors. The most common symptoms for brain tumor would usually be headaches, memory problems, numbness or tingling in certain parts of the body like the legs or arms. Other symptoms are walking and balancing problems, vomiting, seizures, personality change, and can also affect their vision, speech, and hearing. After many tests were taken to figure out the cause of brain tumors, there were no evidences that could support the exact cause. Even though there are no evidences for the exact cause, brain tumors can occur at any age. There are certain types of tumors that fall into the children and adult categories. In the field of brain tumors there are over 120 types of brain tumors that occur in different size and location o f the brain. In oncology, this typically involves differentiating between tumor types and grades, or some type of discrete outcome prediction (Cruz-Barbosa Vellido). Some types of brain tumors that differ from one Brain Tumors Page Number: 5 another are Ependymomas, Optic Neuroma (adults), Pituitary Tumor, Craniopharyngioma, Pediatric Brain Tumor, Astrocytoma (adults), Rhabiod Tumor, Meningioma (adults), Brain Stem Glioma, etc. In adults, the most common types of brain tumors would be Astrocytoma, Meningoma, and also Oligodendroglioma. In adults about half of all CNS tumors are malignant, whereas in pediatric patients; more than 75% are malignant (Khoshnevisan). The most common tumors in children would be Ependyoma, Medulloblastoma, grade 1 or 2 Astrocytoma, and also Brain Stem Glioma. When a person is diagnosed with a certain type of brain tumor then this will help them go to the next step, which is treatment. Treatments are the first thing to do when a person is diagnosed. Just like symptoms, treatment also depends on the type, size, and location of the tumor. Treatment also depends on the age and health of the patient. When treating for brain tumors, they usually go straight to removal surgery (-ectomy), that surgically removes the tumor from the brain. If this procedure is not successful then they go to the next step which is radiation therapy, and chemotherapy (chemo-, drug, -therapy, treatment), which means drug treatment. For example, in chemotherapy there is a drug to fight off brain tumors that can go through the Blood-brain barriers (BBB). Major obstacles for brain tumor treatment including the structure of BBB and efflux transporters, and the efforts that have been used to circumvent BBB Brain Tumors Page Number: 6 and deliver drugs in the brain. In brain tumors, the delivery of anticancer drug is difficult due to presence of the BBB, which acts as physical and physiologic obstacles for delivery of drugs to the brain. Also, cancer chemotherapy is useful for a variety of brain tumors including Lymphomas, Medulloblastomas, Germ Cell Tumors, and Gliomas (Thakur, Gahane, Bhadoriya, Jain S., Jain R., Mishra). Due to the treatments, they always form a high or low risk factor. One of the risk factors a patient can go through is ionizing radiation because, of the high doses of x-rays. Ionizing radiation it directly to the head and a high dose of x-rays increases the risk for affecting the patient. No matter what are always risks when treating a illness. This diagnosis is very important to me because it relates to my little niece. Her name is Cassandra, she is 15 right now and I love her more than anything in the world. We didnt find out that she had a brain tumor until she was 3 years old. The type of brain tumor she has is Craniopharyngioma, which is a benign tumor that develops near the pituitary gland. When the pituitary gland hormone is damaged it imbalances and leads to excessive thirst, excessive urination, and stunt growth. This type of brain tumor can also damage the optic nerves that can cause visual problems, and have a possibility to increase after surgery. We were very heart broken when our family found out that my niece had a brain tumor. The first thing they tried Brain Tumors Page Number: 6 to do was removal surgery, which was not a success. Removal surgery did not work because they could only take some parts of the tumor out. If they do the procedure and took the whole tumor out, then she would be completely blind. They tried many ways to remove this tumor without the risk factor of becoming blind but they just couldnt do it. When they removed some of the brain tumor, it caused her to be blind in her left eye. She is much smaller than her normal group age, so the brain tumor did affect her stunt growth. After knowing this, we knew that her tumor would just keep growing for the rest of her life. Every time the tumor grows, she has to go to surgery and only take some of the brain tumor out. To help fight off the brain tumor from growing she takes chemotherapy. My niece went through so many surgeries throughout her life that we just couldnt keep count of them anymore. It hurts me that my niece has to go through hell every time her tumor grows back. She went through so muc h surgery that she had to wear helmets to protect the part where the skull was removed. Also, they went through her skull so much that they cant do surgery there anymore. They tried do the procedure in other ways like the nostril but her nose was too small. Her last surgery was probably 5 to 6 months ago, so eventually her tumor will be growing back soon. To keep her positive and everyone else position every year we go to the Ride for Kids, which is when hundreds of people come together with their motorcycles and ride for the kids that have brain tumors. We always ride on the motorcycles at Brain Tumors Page Number: 7 the event and at the end; we do a fundraiser to help find a way to overcome this disease. My niece is doing a lot better now that she is older, she is going to Rome Free Academy, and she is in variety cheerleading for RFA. I know my niece has been through a lot but no matter what our family will always be by her side. From my personal experiences, brains tumors can affect the patient emotionally and physically and can also emotionally affect the family. Brain tumors can be very harmful and can ruin everything from health to personalities, and daily routines. If nothing went wrong when the body forms new cells or removes the old and damaged cells, then it would not cause a mass of tumor. Brain tumors can physically affect a person by different types of symptoms. Identify the tumor and the type of tumor can help many patients take care of this disease. Most of the time removal surgery will solve the problem but, if not the health care field tries to find other ways to destroy certain types of brain tumors. It all depends on what type of brain tumor it is, the size, and the location the tumor is occurring. When being diagnosis with brain tumors there are many obstacles that you have to go through in order to stop the tumor from increasing. There are many difficult processes and effects that can take toll on a person with this illness. This certain type of disease can be life threatening Brain Tumors Page Number: 8 and, can a change a persons all around life. Work Cited Ciobanu, A., Miron, I., Tansanu, I. I., Dumitrescu, G., Indrei, A.(2011). PEDIATRIC BRAIN TUMORS MORPHOLOGICAL FINDINGS AND PROGNOSTIC FACTORS.Romanian Journal Of Functional Clinical, Macro- Microscopical Anatomy Of Anthropology /Revista Romà ¢na De Anatomie Functionala Si Clinica, Macro Si Microscopica Si De Antropologie, 10(4), 499-503. CRUZ-BARBOSA, R., VELLIDO, A. (2011). SEMI-SUPERVISED ANALYSIS OF HUMAN BRAIN TUMOURS FROM PARTIALLY LABELED MRS INFORMATION, USING MANIFOLD LEARNING MODELS. International Journal Of Neural Systems, 21(1), 17-29. Khoshnevisan, A. (2012). An overview of therapeutic approaches to brain tumor stem cells.Medical Journal Of The Islamic Republic Of Iran, 26(1), 31-40. Thakur, A., Gahane, A., Bhadoriya, S., Jain, S., Jain, R., Mishra, H. (2011). Major hurdles for brain tumour therapy and the ways to overcome them: A review. Journal Of Pharmacy Research, 4(5), 1315-1318.

Friday, October 25, 2019

The Computer Nut :: essays research papers

Title: â€Å"The Computer Nut† Author: Betsy Byars Setting: â€Å"The Computer Nut† takes place in Kate’s small town. Overall, the different settings are in her house, in school, at a carwash, at Willie Lomax’s house, her dad’s office, a pep rally at her school’s football rally, and that’s basically where all the action takes place. Most of the time, the action takes place during the day. Towards the ending, however, most of the action takes place at night around 8 pm- 9pm. Major Characters: The main character of â€Å"The Computer Nut† is Kate. Kate is like any other kid. She is obsessed with computers, she has red hair, and she is an average middle school student. She is receiving messages from an â€Å"alien† who calls himself BB-9. Willie Lomax is the boy who helps find out who is sending Kate messages over the computer. Willie is also Kate’s crush and he is the only one who is truly willing to help Kate find out who really is sending her messages over the computer. He is around Kate’s height, chubby, he has reddish/blondish hair, and is very interested in Kate’s mystery â€Å"alien.† BB-9 is the self-proclaimed â€Å"alien comedian† who wants to come down to Earth to make people laugh, since Earth is the only planet in the universe where people laugh. He is an adult’s age and can take form as anything he wants. He was once a cow on another mission to Earth. A physical description is not availa ble. And lastly, Linda is Kate’s best friend. She is short, has brown hair, and very humorous. Plot Summary: One day, for an art project, Kate is just drawing a picture of herself on her dad’s computer in her dad’s office. After she is all done with her self-portrait, she receives a message from a strange person who later reveals himself as BB-9. BB-9 is an alien in search of a good laugh on Earth, which he says is the only planet where people laugh. After a series of message, Kate hopes the person contacting her is her secret crush, Willie Lomax, who just so happens to know about computers. Kate is determined to find out who it is.   Ã‚  Ã‚  Ã‚  Ã‚  When Kate’s best friend, Linda, finds out about the messages, she goes on and on and insists about how it HAS to be Frank Wilkins, a boy who told Kate he loved her at band camp a couple years back.

Thursday, October 24, 2019

Ontela Pickdeck A Essay

I would focus in priority on the teenagers, then on the young professionals and ultimately on the parents and the elderly. As a matter of fact, teenagers are the part of the population both most sensitive to fad phenomena and best at using new technologies. 1) Regina, the Teen First segment to target The teenagers’ generation is and has always been very sensitive to fashion. Moreover, immerged in the Internet Age since their childhood, they will always be looking for the state-of-the-art device or application (and will always have the time to do it). Thus they will be curious about the Ontela PickDeck for its revolutionary aspect and its ability to link all their devices rapidly. If their friends install the application they will surely do so. On the other hand, they are very good at using new technologies so they will not have the apprehension of dealing with that one. More importantly, they will be the PickDeck best ambassadors to their parents (segment most difficult to target) afterwards, and able to install it for them. The segment’s main default is that they do not own their own money. 2) Steve, the Young Professional Second segment to target The young professionals’ generation did not grow with the Internet Age so they master it a bit less. They are less curious and have less time so they would use it only if they can see a competitive advantage for their work but they generally work in the old-fashioned way. They will focus on the following qualities of the application: the rapid-sharing, the ease of use and the fact they can use it from everywhere. They would follow the movement if the application was spreading among their colleagues. The main default of this segment is their lack of time both to study advertisement and to learn how to use the application (relatively high apprehension to use it). 3) Sarah, the Parent Last segment to target The parents’ generation does not understand anything about new technologies. They generally cannot even use a third of their devices’ options. However, once installed on their smartphones they will certainly enjoy it. A non-exhaustive defaults’ list of the segment may contain: The high apprehension to use such an application The lack of time to consider buying it The low sensitivity to fads The inability to install it themselves That is why PickDeck needs children as ambassadors 2) Create positioning statements for you two first chosen target personas 1) Regina, the Teen Key themes: A state-of-the-art technology A permanent connection everywhere, at any time A connection with all your friends via social networks Ambassadors to the family â€Å"My new product PickDeck is the state-of-the-art way to have the pictures you take directly available on all your devices and social networks. Everywhere, anytime, the wireless technology will allow you to keep sharing your best moments with your friends and family.† 2) Steve, the Young Professional Key themes: A permanent connection everywhere, at any time A fast and efficient application An easy-learning application Time â€Å"My new product PickDeck is the easiest way to upload the pictures you take automatically on your devices, it is definitely time-efficient. Everywhere, anytime, the wireless technology will allow you to keep improving your efficiency and sharing with your customers and friends.†

Tuesday, October 22, 2019

Documentary film Super Size Me

Crucial health information is brought to the general public’s attention, when Morgan Spurlock directs and stars in the documentary film Super Size Me. After the obesity epidemic that broke out in the early 2000’s, Spurlock wonder’s what would happen if he were to consume only McDonald’s for breakfast, lunch and dinner for thirty days. This experiment raised many eyebrows to what is really reflected as healthy food. Therefore, due to Spurlock’s study a question came to mind; Should McDonald’s place health warning labels on their so-called food products?Yes, all McDonald’s should place health warning labels’ on their products of food. Spurlock proves that McDonald’s is not safe to consume, because at the end of his experiment he gained twenty four and a half pounds, had a thirteen percent increase in body mass, a  cholesterol  level of 230, elevated mood swings, fat buildup in his liver and sexual dysfunction. Many crit ics say that because Spurlock was not exercising regularly and was intentionally consuming an average of 5,000 calories a day, that anybody would have had the same results.Nonetheless after Spurlock carried out his experiment, he proved his case which is, walking 5,000 steps a day and consuming 5,000 calories a day of just McDonald’s is dangerous from every view and McDonald’s should place warning labels on all their food that is sold to the public. Though warning labels’ on McDonalds food would not harm business as much as corporate thinks it will, in the film Super Size Me, Spurlock approaches random members on the street of Manhattan, New York and ask if they know how bad McDonalds is for them and if so, why do they continue to eat it?Every person that was addressed by Spurlock stated yes they do know fast food restaurants are the main cause for health problems, but they still love to eat out. Proving that even the informed American concisely makes the decisi on to eat out rather than making a fresh meal at home. In the end, Spurlock’s film was a success when it came to getting his message across, which is, be informed and stay healthy.